monocyte :
- 3-4x larger than a mature RBC
- Lower nuclear to cytoplasmic ratio because of increased cytoplasm
- Kidney shaped Indented Nucleus with mature chromatin (clumped)
- Nucleoli are absent
- Cytoplasm is abundant, gray to pale blue and with rare to no granules
- vacuoles are commonly noted in cytoplasm.
reactive lymphocyte :
- 2-4x larger than a mature RBC
- Increased amount of light blue cytoplasm
- Nucleoli usually absent
- Cytoplasm is usually indented by surrounding RBCs
- Granules are usually absent.
so in conclusion :
- mono : cell is larger , lower N\C ratio , finer nuclear chromatin
- reactive lamphocyte :cell is smaller , condensed chromatin ,higher N\C ratio